Space Shuttle Payloads: Kennedy Space Center was the hub for the final preparation and launch of the space shuttle and its payloads. The shuttle carried a wide variety of payloads into Earth orbit. Not all payloads were installed in the shuttle's cargo bay. In-cabin payloads were carried in the shuttle's middeck. Cargo bay payloads were typically large payloads which did not require a pressurized environment, such as interplanetary space probes, earth-orbiting satellites, scientific laboratories and International Space Station trusses and components. Poster designed by Kennedy Space Center Graphics Department/Greg Lee. Credit: NASA KSC-2012-1863

The Space Shuttle program was the United States government's manned launch vehicle program from 1981 to 2011, administered by NASA and officially beginning in 1972. The Space Shuttle system—composed of an orbiter launched with two reusable solid rocket boosters and a disposable external fuel tank— carried up to eight astronauts and up to 50,000 lb (23,000 kg) of payload into low Earth orbit (LEO). When its mission was complete, the orbiter would re-enter the Earth's atmosphere and lands as a glider. Although the concept had been explored since the late 1960s, the program formally commenced in 1972 and was the focus of NASA's manned operations after the final Apollo and Skylab flights in the mid-1970s. It started with the launch of the first shuttle Columbia on April 12, 1981, on STS-1. and finished with its last mission, STS-135 flown by Atlantis, in July 2011.